PHOTO-2024-01-29-09-33-37

The Golden Gate

Unleash Your Feminine Powers
to Graceful Aging

a guide to living longer and healthier with joy

30 % Profits to Mona Foundation

Amazon Best Seller

Additional Chapter Materials

References & Sources

Further Reading, Resources & Index

Podcasts

References & Sources

Introduction

  1. 'Abdu’l-Bahá, quoted in Wendell Phillips Dodge, 'Abdul-Bahá’s Arrival in America, in Star of the West 3 (April 28, 1912).

Chapter 2

  1. Equality Now: https://www.equalitynow.org/the-middle-east-and-north-africa
  2. Barbara Davis (Zanotti), Patriarchy: A State of War: https://bcrw.barnard.edu/archive/militarism/feminism_the_hope_for_a_future.pdf
  3. Dr. John E. Esslemont, Baha’u’llah and the New Era: https://www.bahai.org/library/other-literature/publications-individual-authors/bahaullah-new-era/1#773046298
  4. Living the Legacy: The Women’s Rights Movement (1848-1998): https://nationalwomenshistoryalliance.org/history-of-the-womens-rights-movement
  5. Shoghi Effendi, God Passes By: https://www.bahai.org/library/authoritative-texts/shoghi-effendi/god-passes-by/4#439208213
  6. ibid.
  7. ibid.
  8. Iranian Human Rights Activist Wins Nobel Peace Prize: https://www.usip.org/publications/2023/10/iranian-human-rights-activist-wins-nobel-peace-prize
  9. “Woman, life, freedom!” An activist continues her fight for women’s rights: https://www.ohchr.org/en/stories/2022/11/woman-life-freedom-activist-continues-her-fight-womens-rights
  10. ibid
  11. The Iran Primer: https://iranprimer.usip.org/blog/2023/mar/08/mass-poisoning-schoolgirls-iran
  12. Olympic Analysis, Forced hijab and female athletes in post-revolutionary Iran: https://olympicanalysis.org/section-5/forced-hijab-and-female-athletes-in-postrevolutionary-iran
  13. The World Bank: https://data.worldbank.org/indicator/SE.ADT.1524.LT.FE.ZS
  14. Tablets of Bahá’u’lláh: https://www.bahai.org/library/authoritative-texts/bahaullah/tablets-bahaullah/5#009015192
  15. Mahsa Amini: The Spark That Ignited A Women-Led Revolution, Maggie McGrath, Forbes https://www.forbes.com/sites/maggiemcgrath/2022/12/06/mahsa-amini-the-spark-that-ignited-a-women-led-revolution/?sh=27130dbb5c3d
  1. Oregon Secretary of State: https://sos.oregon.gov/archives/exhibits/suffrage/Pages/bio/duniway.aspx

Chapter 3

  1. Precedence Research, The Botulinum Toxin Market: https://www.precedenceresearch.com/botulinum-toxin-market
  2. 2022 ASPS Procedural Statistics Release: https://www.plasticsurgery.org/documents/News/Statistics/2022/plastic-surgery-statistics-report-2022.pdf
  3. Statista: https://www.statista.com/statistics/281368/us-expenditures-on-major-surgical-cosmetic-procedures/#statisticContainer
  4. Curtin, et al, Suicide and Homicide Death Rates Among Youth and Young Adults Aged 10–24: United States, 2001–2021: https://stacks.cdc.gov/view/cdc/128423
  5. Audette, et al, Quality of Life: A Cross-National Analysis of the Effect of Gender Equality on Life Satisfaction: https://link.springer.com/article/10.1007/s10902-018-0042-8

Chapter 4

  1. T.S. Sathyanarayana Rao et al, The Biochemistry of Belief: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802367/
  2. Ibid.
  3. Moseley et al, A Controlled Trial of Arthroscopic Surgery for Osteoarthritis of the Knee: https://www.nejm.org/doi/full/10.1056/nejmoa013259
  1. T.S. Sathyanarayana Rao et al, The Biochemistry of Belief: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802367/
  2. Deepak Chopra, Ageless Body, Timeless Mind: https://scholar.google.com/citations?view_op=view_citation&hl=en&user=4Bp70u0AAAAJ&citation_for_view=4Bp70u0AAAAJ:TQgYirikUcIC
  1. T.S. Sathyanarayana Rao et al,, The Biochemistry of Belief: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2802367/
  2. M L Bowden, N J Hopwood, Psychosocial Dwarfism: https://pubmed.ncbi.nlm.nih.gov/7123443/

Chapter 5

  1. Adolfsson et al, Guilt and Emptiness: Women’s Experiences of Miscarriage: https://pubmed.ncbi.nlm.nih.gov/15354621/
  2. Cerna et al, Guilt, Shame and their Associations with Chronic Diseases in Czech Adults: https://pubmed.ncbi.nlm.nih.gov/34402335/
  3. Abrams, R. D., & Finesinger, J. E., Guilt Reactions in Patients with Cancer: https://psycnet.apa.org/record/1954-08910-001
  4. O’Mahoney et al, The prevalence and long-term health effects of Long Covid among hospitalized and non-hospitalized polulations: a systematic review and meta-analysis: https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00491-6/fulltext
  5. Savage et al, Humor, laughter, learning, and health! A brief review: https://journals.physiology.org/doi/full/10.1152/advan.00030.2017
  6. Monit Cheung & Carol A. Leung, Laughter Yoga as a Social Work Intervention: https://www.tandfonline.com/action/showCitFormats?doi=10.1080%2F00377317.2020.1819938
  7. Medaris, Women say they’re stressed, misunderstood, and alone: https://www.apa.org/topics/stress/women-stress
  8. Suss & Ehlert, Psychological Resilience During the Perimenopause: https://pubmed.ncbi.nlm.nih.gov/31787147/
  9. Prestia, The Moral Obligation of Nurse-Leaders: Covid-19: https://pubmed.ncbi.nlm.nih.gov/32313516/
  10. Patterson et al, Moral Distress of Medical Family Therapists and their Physician Colleagues During the Transition to Covid-19: https://pubmed.ncbi.nlm.nih.gov/33751596/
  11. Min et al, Characteristics Associated with Low Resilience in Patients with Depression and/or Anxiety Disorders: https://pubmed.ncbi.nlm.nih.gov/22485024/
  12. Bartres-Faz et al, Meaning in Life: Resilience Beyond Reserve: https://pubmed.ncbi.nlm.nih.gov/29793549/

Chapter 6

Quote Page 114: "To everything there is a season, and a time..." Abdu'l-Baha referencing Ecclesiastes 3 in Bible King James Version

  1. Ilene S. Cohen, Trusting the Process, Psychology Today: https://www.psychologytoday.com/gb/blog/your-emotional-meter/201809/trusting-the-process
  2. Lyons-Ruth et al, Developmental costs associated with early maternal withdrawal https://srcd.onlinelibrary.wiley.com/doi/10.1111/cdep.12442
  3. Park et al, The Healing of the Seven Generations: https://healingofthesevengenerations.ca/about/history/#_ftn19
  4. Lavoie, Trauma Can be Passed Down Through Generations: https://ucalgary.ca/news/trauma-can-be-passed-down-through-generations

Chapter 7

  1. Margois et al, Potential Association Between the Oral Tetracycline Class of Antimicrobials used to Treat Acne and Inflammatory Bowel Disease: https://journals.lww.com/ajg/abstract/2010/12000/potential_association_between_the_oral.16.aspx
  2. Robertson et al, Science Direct: https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/salicylic-acid
  3. Haynes, A Pioneer in the Development of Aspirin: https://pharmaceutical-journal.com/article/opinion/a-pioneer-in-the-development-of-aspirin
  4. The History of Aspirin: https://en.wikipedia.org/wiki/History_of_aspirin
  5. Martin, Coal Tar Antipyretics: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8939603/pdf/atlantamsj141493-0043.pdf
  6. Phenacetin – information sheet: https://www.canada.ca/en/health-canada/services/chemical-substances/fact-sheets/chemicals-glance/phenacetin.html#
  7. Wikipedia: https://en.wikipedia.org/wiki/Phenacetin
  8. Wikipedia: https://en.wikipedia.org/wiki/Acetanilide
  9. Agrawal et al, Acetaminophen Toxicity: https://www.ncbi.nlm.nih.gov/books/NBK441917/#:~:text=Acetaminophen%20toxicity%20is%20the%20second,year%20in%20the%20United%20States
  10. Jaeschke et al, Novel Therapeutic Approaches Against Acetaminophen-induced Liver Injury and Acute Liver Failure: https://pubmed.ncbi.nlm.nih.gov/31926003/
  11. Ilekis, NIH-funded study suggests acetaminophen exposure in pregnancy linked to higher risk of ADHD, autism: https://www.nih.gov/news-events/news-releases/nih-funded-study-suggests-acetaminophen-exposure-pregnancy-linked-higher-risk-adhd-autism
  12. Sakulchit et al, Acetaminophen Use and Asthma in Children: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349720/
  13. Centers for Disease Control, Facts About Hypertension: https://www.cdc.gov/bloodpressure/facts.htm
  14. Dev Nutr, Prevalence of High Cholesterol Among the Adult US Population: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9194142/
  15. Matyori et al, Statins Utilization Trends and Expenditures in the U.S. Before and After the Implementation of the 2013 ACC/AHA Guidelines: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203693/
  16. Yang et al, Trends and Characteristics of Blood Pressure Prescription Fills Before and During the COVID-19 Pandemic in the United States: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10345475/
  17. Mikulic, Distribution of Global Pharmaceutical Market Revenue from 2010 to 2022 by region: https://www.statista.com/statistics/275535/distribution-of-global-pharmaceutical-market-revenue/
  18. European Federation of Pharmaceutical Industries and Associations, The Pharmaceutical Industry in Figures: https://www.efpia.eu/media/637143/the-pharmaceutical-industry-in-figures-2022.pdf
  19. Ouyang et al, Increased Mortality Trends in Patients With Chronic Non-Communicable Diseases and Co-morbid Hypertension in the United States, 2000-2019: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9309719/#:~:text=Non%2Dcommunicable%20diseases%20(NCDs)%20are%20the%20leading%20causes%20of,%2C%204%25)%20(2
  20. Centers for Disease Control and Prevention, Health and Economic Costs of Chronic Diseases: https://www.cdc.gov/chronicdisease/about/costs/index.htm
  21. Brody et al, Antidepressant Use Among Adults: United States, 2015-2018: https://www.cdc.gov/nchs/products/databriefs/db377.htm
  22. Pratt et al, Antidepressant Use in Persons Aged 12 and Over: United States, 2005-2008: https://www.cdc.gov/nchs/products/databriefs/db76.htm
  23. Wehrwein, Astounding Increase in Antidepressant Use by Americans: https://www.health.harvard.edu/blog/astounding-increase-in-antidepressant-use-by-americans-201110203624
  24. American Thyroid Association, Clinical Thyroidology for the Public,: https://www.thyroid.org/patient-thyroid-information/ct-for-patients/october-2020/vol-13-issue-10-p-8-9/
  25. Wen et al, Unraveling the impact of Omega-3 polyunsaturated fatty acids on blood-brain barrier (BBB) integrity and glymphatic function: https://pubmed.ncbi.nlm.nih.gov/37914102/
  26. Cappus-McCendie et al, Omega-3 PUFA Metabolism and Brain Modifications During Aging: https://www.sciencedirect.com/science/article/abs/pii/S0278584619300971?via%3Dihub
  27. Serrano-Pozo et al, Effects of Simvastatin on Cholesterol Metabolism and Alzheimer Disease Biomarkers: https://pubmed.ncbi.nlm.nih.gov/20473136/
  28. Alzheimer’s Association, Alzheimer's Facts and Figures: https://www.alz.org/alzheimers-dementia/facts-figures#:~:text=More%2520than%25206%2520million%2520Americans%2520of%2520all%2520ages%2520have%2520Alzheimer%2527s,older%2520(10.7%2525)%2520has%2520Alzheimer%2527s.
  29. Alzheimer’s Association, 2023 Alzheimer’s disease facts and figures: https://doi.org/10.1002/alz.13016
  30. Buntz, The 50 best-selling pharmaceuticals of 2022: https://www.drugdiscoverytrends.com/50-of-2022s-best-selling-pharmaceuticals/#:~:text=Meanwhile%252C%2520the%2520heavyweight%2520tumor%2520necrosis,the%252050%2520best%252Dselling%2520pharmaceuticals.
  31. Centers for Disease Control: Women and Autoimmune Diseases: https://wwwnc.cdc.gov/eid/article/10/11/04-0367_article#:~:text=Autoimmune%2520diseases%2520affect%2520approximately%25208,infections%2520can%2520induce%2520autoimmune%2520disease.
  32. YouGov: Doctor Visits 2022 1000 US Adult Citizens: https://d3nkl3psvxxpe9.cloudfront.net/documents/crosstabs_Doctor_Visits.pdf
  33. Georgetown Health Policy Institute: Prescription Drugs: https://hpi.georgetown.edu/rxdrugs/
  34. Realizing the Promise of Personalized Aging: https://hbr.org/2007/10/realizing-the-promise-of-personalized-medicine
  35. AAMCNews: The nation’s medical schools grow diversity: https://www.aamc.org/news/nation-s-medical-schools-grow-more-diverse
  36. AAMC: Total Graduates by US MD-Granting Medical School: https://www.aamc.org/media/6111/download?attachment

Chapter 8

  1. Dharap et al, Incidence and Risk Factors of Postoperative Complications in General Surgery Patients: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714582/
  2. Tevis et al, Post-operative complications and implications on patient-centered outcomes: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3637983/
  3. Dharap et al, Incidence and Risk Factors of Postoperative Complications in General Surgery Patients: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9714582/
  4. Semeniuk et al, Integrative Oncology and the Clinical Care Network: https://pubmed.ncbi.nlm.nih.gov/37373639/
  5. Cybulska et al, Depressive Symptoms Among Middle-Age Women: Understanding the Cause: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7824332/
  6. Johansson et al, Investigating the Effect of Estradiol Levels on the Risk of Breast, Endometrial and Ovarian Cancer: https://academic.oup.com/jes/article/6/8/bvac100/6619509
  7. Rodriguez-Lara et al, Influence of Estrogen in Non-Small Cell Lung Cancer and its Clinical Implications: https://jtd.amegroups.org/article/view/18368/html#:~:text=In%20addition%2C%20estrogen%20can%20promote,and%20high%20expression%20of%20ERβ
  8. Desai et al, Autoimmune Disease in Women: Endocrine Transition and Risk across Life Span: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501433/
  9. Root-Bernstein et al, Estrogen binds to Insulin and Insulin Receptor Decreasing Insulin Binding in vitro: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4104309/
  10. D’Arrigo, Risk of Depression May Increase During First Two Years of Oral Contraceptive Use: https://psychnews.psychiatryonline.org/doi/full/10.1176/appi.pn.2023.09.9.6#:
  11. Lloyd, Hormonal Contraception and Suicide: A New Dimension of Risk: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6193788/
  12. Trenor et al, Hormonal Contraception and Thrombotic Risk: A Multidisciplinary Approach: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3025417/
  13. Kaminski et al, Cardiovascular Risk and the Use of Oral Contraceptives: https://pubmed.ncbi.nlm.nih.gov/24464000/
  14. Dehghan et al, Oral Contraceptive Steroids Promote Papillary Thyroid Cancer Metastasis by Targeting Angiogenesis and Epithelial-Mesenchymal Transition: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800459/
  15. Sorensen, Prevention of diabetes mortality at ages younger than 25 years: access to medication and high-quality health care: https://doi.org/10.1016/S2213-8587(22)00009-2
  16. Parker et al, Economic Costs of Diabetes in the U.S. in 2022: https://pubmed.ncbi.nlm.nih.gov/37909353/#:~:text=Results%3A%20The%20total%20estimated%20cost,indirect%20costs%20attributable%20to%20diabetes.

Chapter 9

  1. Gonzalez-Diaz et al, Psychoneuroimmunoendocrinology: Clinical Implications: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460476/
  2. Ibid
  3. Yue, Biology of the Extracellular Matrix: An Overview: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4185430/#:~:text=The%20extracellular%20matrix%20(ECM)%20is,the%20mechanical%20properties%20of%20tissues.
  4. Psychiatric Times: Being Human: An Interview with Daniel J. Siegel, MD: https://www.psychiatrictimes.com/view/being-human-interview-daniel-j-siegel-md
  5. Sage, Electromagnetic Fields, Pulsed Radiofrequency Radiation and Epigenetics: https://srcd.onlinelibrary.wiley.com/doi/10.1111/cdev.12824
  6. Venditti et al, Molecules of Silence: Effects of Meditation on Gene Expression and Epigenetics: https://www.frontiersin.org/journals/psychology/articles/10.3389/fpsyg.2020.01767/full
  7. Borg et al, Psychology Today: A New Understanding of Compassionate Empathy: https://www.psychologytoday.com/us/blog/irrelationship/201408/new-understanding-compassionate-empathy
  8. Galleri Early Detection Cancer test: https://www.galleri.com
  9. Rahma et al, Electrodermal Activity of Measuring Cognitive and Emotional Stress Level: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215837/

Chapter 10

  1. Green, Your Socks Are Made With Plastic and Could Be Loaded With Dangerous BPA: https://www.sfchronicle.com/opinion/openforum/article/Your-socks-are-made-with-plastic-and-could-be-16680614.php
  2. Ruiz & Patisaul, Endocrine-Disrupting Chemicals (EDCs): https://www.endocrine.org/patient-engagement/endocrine-library/edcs
  3. Green, Your Socks Are Made With Plastic and Could Be Loaded With Dangerous BPA: https://www.sfchronicle.com/opinion/openforum/article/Your-socks-are-made-with-plastic-and-could-be-16680614.php
  4. United States Environmental Agency, Human Exposure Health: https://www.epa.gov/report-environment/human-exposure-and-health
  5. The American Cancer Society, Radiation Therapy Side Effects: https://www.cancer.org/cancer/managing-cancer/treatment-types/radiation/effects-on-different-parts-of-body.html
  6. Mento et al, Negative Emotions in Skin Disorders: A Systematic Review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7498125/
  7. Myers et al, Emunctorology: Synthesising Traditional Naturopathic Practice With Natural Science
  8. Castell et al, Metabolism and bioactivation of toxicants in the lung. The in vitro cellular approach: https://pubmed.ncbi.nlm.nih.gov/16092727/
  9. Khan, Lymphatic System in the Brain: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9272342/
  10. Wisniewska et al, Review on the Lymphatic Vessels in the Dental Pulp: https://www.mdpi.com/2079-7737/10/12/1257
  11. Sepulveda et al, Periodontal Disease, Systemic Inflammation and the Risk of Cardiovascular Disease: https://pubmed.ncbi.nlm.nih.gov/29903685/
  12. Wahid et al, Bidirectional Relationship between Chronic Kidney Disease & Periodontal Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809193/
  13. Saini, Oral Health Links Breast Cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3178963/
  14. Freudenheim et al, Periodontal disease and breast cancer: Prospective cohort study of postmenopausal women: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4713270/
  15. Brod et al, ’As above, so below’: Examining the interplay between emotion and the immune system: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212945/
  16. Hodges et al, Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Applications: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488002/
  17. Ibid
  18. Ibid
  19. Dasanayaka et al, Associations of meditation with telomere dynamics: A case-control study in healthy adults: https://pubmed.ncbi.nlm.nih.gov/37519381/
  20. Chiax et al, Differential DNA methylation in experienced meditators after an intensive day of mindfulness-based practice: implications for immune-related pathways: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010561/
  21. Porter et al, Mindfulness Meditation Interventions for Long COVID: Biobehavioral Gene Expression and Neuroimmune Functioning: https://www.dovepress.com/mindfulness-meditation-interventions-for-long-covid-biobehavioral-gene-peer-reviewed-fulltext-article-NDT
  22. Yang et al, State and Training Effects of Mindfulness Meditation on Brain Networks Reflect Neuronal Mechanisms of its Antidepressant Effect: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779536/

Chapter 11

  1. Ryman et al, Microbiome–gut–brain dysfunction in prodromal and symptomatic Lewy body diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9886597/
  2. Guinane et al, Role of the gut microbiota in health and chronic disease: understanding a hidden metabolic organ: https://journals.sagepub.com/doi/10.1177/1756283X13482996
  3. Baker et al, Estrogen-gut microbiome axis: Physiological and clinical implications: https://pubmed.ncbi.nlm.nih.gov/28778332/
  4. Kermgard et al, Gut microbiome, parathyroid hormone, and bone: https://pubmed.ncbi.nlm.nih.gov/34027903/
  5. Wiertsema et al, The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies: https://www.mdpi.com/2072-6643/13/3/886
  6. Chakraborty, Altered gut microbiota patterns in COVID-19: Markers for inflammation and disease severity: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9280735/
  7. Craciun et al, The Relationships Between Gut Microbiota and Diabetes Mellitus, and Treatments for Diabetes Mellitus: https://www.mdpi.com/2227-9059/10/2/308
  8. Kania et al, Diabetes as a risk factor of death in hospitalized COVID-19 patients – an analysis of a National Hospitalization Database from Poland, 2020: https://www.frontiersin.org/journals/endocrinology/articles/10.3389/fendo.2023.1161637/full
  9. Zhang et al, Gut Microbiota Dysbiosis Correlates With Long COVID-19 at One-year Discharge: https://pubmed.ncbi.nlm.nih.gov/37069814/
  10. Greathouse et al, Diet-microbiome interactions in cancer treatment: Opportunities and challenges for precision nutrition in cancer: https://www.sciencedirect.com/science/article/pii/S1476558622000276?via%3Dihub
  11. Rios-Covian et al, From Short-to Long-Term Effects of C-Section Delivery on Microbiome Establishment and Host Health: https://www.mdpi.com/2076-2607/9/10/2122
  12. Gaufin et al, The importance of the microbiome in pediatrics and pediatric infectious diseases: https://journals.lww.com/co-pediatrics/abstract/2018/02000/the_importance_of_the_microbiome_in_pediatrics_and.18.aspx
  13. Laue et al, The Developing Microbiome From Birth to 3 Years: The Gut-Brain Axis and Neurodevelopmental Outcomes: https://www.frontiersin.org/articles/10.3389/fped.2022.815885/full
  14. Zhu et al, The Relationship Between the Gut Microbiome and Neurodegenerative Diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34216356/
  15. Ibid
  16. Gates et al, Modifying the diet and gut microbiota to prevent and manage neurodegenerative diseases: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9514114/
  17. Turpin et al, Mediterranean-Like Dietary Pattern Associations With Gut Microbiome Composition and Subclinical Gastrointestinal Inflammation: https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/34216356/
  18. Solch et al, Mediterranean diet adherence, gut adherence, gut microbiota, and Alzheimer’s or Parkinson’s disease risk: A systematic review: https://pubmed.ncbi.nlm.nih.gov/35144237/
  19. Bicknell et al, Neurodegenerative and Neurodevelopmental Disease and the Gut-Brain Axis: The Potential of Therapeutic Targeting of the Microbiome: https://www.mdpi.com/1422-0067/24/11/9577
  20. Di Meo et al, Curcumin, Gut Microbiota, and Neuroprotection: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6835970/
  21. Scazzocchio et al, Interaction between Gut Microbiota and Curcumin: A Key of Understanding for the Health Effects of Curcumin: https://pubmed.ncbi.nlm.nih.gov/32824993/
  22. Carabotti et al, The gut-brain axis: interactions between enteric microbiota, central and enteric nervous systems: https://pubmed.ncbi.nlm.nih.gov/25830558/
  23. Plummer et al, Gut-brain pathogenesis of post-acute COVID-19 neurocognitive symptoms: https://www.frontiersin.org/journals/neuroscience/articles/10.3389/fnins.2023.1232480/full
  24. Ibid
  25. Sun et al, Gut hormones in microbiota-gut-brain cross-talk: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147657/
  26. Baker et al, Estrogen-gut microbiome axis: Physiological and clinical implications: https://pubmed.ncbi.nlm.nih.gov/28778332/
  27. Ervin et al, Gut microbial β-glucuronidases reactivate estrogens as components of the estrobolome that reactivate estrogens: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6901331/
  28. Baker et al, Estrogen-gut microbiome axis: Physiological and clinical implications: https://pubmed.ncbi.nlm.nih.gov/28778332/
  29. Kwa et al, The Intestinal Microbiome and Estrogen Receptor–Positive Female Breast Cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017946/
  30. Baker et al, Estrogen-gut microbiome axis: Physiological and clinical implications: https://pubmed.ncbi.nlm.nih.gov/28778332/
  31. Filippone et al, Endocrine Disruptors in Food, Estrobolome and Breast Cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10178963/
  32. Altern Med Rev, Calcium-D-Glucarate: https://pubmed.ncbi.nlm.nih.gov/12197785/
  33. Maier, Oral Microbiome in Health and Disease: Maintaining a Healthy, Balanced Ecosystem and Reversing Dysbiosis: https://www.mdpi.com/2076-2607/11/6/1453#:~:text=Dysbiosis%20of%20the%20oral%20microbiome,%2C%20and%20diabetes%20%5B12%5D
  34. Santonocito et al, A Cross-Talk between Diet and the Oral Microbiome: Balance of Nutrition on Inflammation and Immune System’s Response during Periodontitis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9227938/
  35. Li et al, Association between the quality of plant-based diets and periodontitis in the U.S. general population: https://onlinelibrary.wiley.com/doi/10.1111/jcpe.13785
  36. Bedouin et al, Large Study Links Gum Disease with Dementia: https://www.nia.nih.gov/news/large-study-links-gum-disease-dementia
  37. Dhadse, The link between periodontal disease and cardiovascular disease: How far we have come in last two decades?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3100856/
  38. Nwizu et al, Periodontal disease and cancer: Epidemiologic studies and possible mechanisms: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7328760/
  39. Martinez-Herrera et al, Association between obesity and periodontal disease. A systematic review of epidemiological studies and controlled clinical trials: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5813989/
  40. Bingham & Moni, Periodontal disease and rheumatoid arthritis: the evidence accumulates for complex pathobiologic interactions: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495574/
  41. Bansal et al, Potential role of periodontal infection in respiratory diseases – a review: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786481/
  42. Pischke et al, High prevalence of periodontal disease in patients with NASH – possible association of poor dental health with NASH severity: https://pubmed.ncbi.nlm.nih.gov/36646168/
  43. Bingham et al, Periodontal disease and rheumatoid arthritis: the evidence accumulates for complex pathobiologic interactions: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4495574/
  44. Baima et al, Periodontitis and risk of cancer: Mechanistic evidence: https://pubmed.ncbi.nlm.nih.gov/38102837/
  45. Zhang et al, The Relationship Between Periodontal Disease and Breast Cancer: From Basic Mechanism to Clinical Management and Prevention: https://pubmed.ncbi.nlm.nih.gov/36794777/
  46. Baima et al, Periodontitis and risk of cancer: Mechanistic evidence: https://pubmed.ncbi.nlm.nih.gov/38102837/
  47. Zhang et al, Combined Non-Invasive Prediction and New Biomarkers of Oral and Fecal Microbiota in Patients with Gastric and Colorectal Cancer: https://www.frontiersin.org/articles/10.3389/fcimb.2022.830684/full
  48. Weiss, Endocrine Disruptors as a Threat to Neurological Function: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3090512/
  49. Denuziere et al, Cerebral concentration and toxicity of endocrine disrupting chemicals: The implications of blood-brain interfaces: https://www.sciencedirect.com/science/article/abs/pii/S0161813X22000523
  50. Das et al, ‘Brain on Fire’: an extraordinary cinematic depiction of the phenomenon of diagnostic overshadowing: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8291295/
  51. Lana et al, Nebulization of glutathione and N-Acetylcysteine as an adjuvant therapy for COVID-19 onset: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349474/
  52. Iskusnykh et al, Glutathione in Brain Disorders and Aging: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746815/
  53. Michalik et al, Multidrug-resistant strains of coagulase-negative staphylococci isolated from patients with chronic sinusitis: https://pubmed.ncbi.nlm.nih.gov/32022700/
  54. Michalik et al, Multidrug resistant coagulase-negative Staphylococcus spp. Isolated from cases of chronic rhinosinusitis in humans. Study from Poland. https://pubmed.ncbi.nlm.nih.gov/34898473/
  55. Becker et al, Emergence of coagulase-negative staphylococci: https://pubmed.ncbi.nlm.nih.gov/32056452/
  56. Dydyk & Gupta, Chronic Pelvic Pain: https://www.ncbi.nlm.nih.gov/books/NBK554585/
  57. Marks et al, Clinical Review of Neuromusculoskeletal Complementary and Alternative Approaches for the Treatment of Chronic Pelvic Pain Syndrome: https://pubmed.ncbi.nlm.nih.gov/35989846/
  58. Macias-Cortes et al, Response to Individualized Homeopathic Treatment for Depression in Climacteric Women with History of Domestic Violence, Marital Dissatisfaction or Sexual Abuse: Results from the HOMDEP-MENOP Study: https://pubmed.ncbi.nlm.nih.gov/29871025/
  59. Teixeira et al, Potentized estrogen in homeopathic treatment of endometriosis-associated pelvic pain: A 24-week randomized, double-blind, placebo-controlled study: https://pubmed.ncbi.nlm.nih.gov/28187404/
  60. Witt et al, Homeopathic treatment of patients with dysmenorrhea: a prospective observational study with 2 year follow-up: https://pubmed.ncbi.nlm.nih.gov/19229544/
  61. Newman, Gut Bacteria: The Surprising Impact of Viruses: https://www.medicalnewstoday.com/articles/325423#Future-possibilities-and-much-more-work

Chapter 12

  1. Zhang, Oxytocin: A key to aetiology and treatment for Autism Spectrum Disorder: https://www.thelancet.com/journals/ebiom/article/PIIS2352-3964(22)00307-3/fulltext
  2. Lerman et al, Oxytocin and cancer: An emerging link: https://www.wjgnet.com/2218-4333/full/v9/i5/74.htm
  3. Ji et al, Oxytocin inhibits ovarian cancer metastasis by repressing the expression of MMP-2 and VEGF: https://www.jcancer.org/v09p1379.htm
  4. Liu et al, The role of the oxytocin system in the resilience of patients with breast cancer: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1187477/full
  5. Stordal, Breastfeeding reduces the risk of breast cancer: A call for action in high-income countries with low rates of breastfeeding: https://onlinelibrary.wiley.com/doi/10.1002/cam4.5288
  6. Babic et al, Association Between Breastfeeding and Ovarian Cancer Risk: https://jamanetwork.com/journals/jamaoncology/fullarticle/2763398
  7. Feixiang et al, The mechanism of oxytocin and its receptors in regulating cells in bone metabolism: https://pubmed.ncbi.nlm.nih.gov/37229246/
  8. Elabd et al, Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration: https://www.nature.com/articles/ncomms5082
  9. Kim et al, Priming of mesenchymal stem cells with oxytocin enhances the cardiac repair in ischemia/reperfusion injury: https://pubmed.ncbi.nlm.nih.gov/21893931/
  10. Lawson, The effects of oxytocin on eating behaviour and metabolism in humans: https://www.nature.com/articles/nrendo.2017.115
  11. Mekhael et al, Evaluating the efficacy of oxytocin for pain management: An updated systematic review and meta-analysis of randomized clinical trials and observational studies: https://www.tandfonline.com/doi/full/10.1080/24740527.2023.2191114
  12. Li et al, Approaches Mediating Oxytocin Regulation of the Immune System: https://www.frontiersin.org/articles/10.3389/fimmu.2016.00693/full
  13. Sharkey et al, Melatonin Synergizes with Oxytocin to Enhance Contractibility of Human Myometrial Smooth Muscle Cells: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2730229/
  14. Chen et al, Thyroid Hormones in Relation to Lead, Mercury, and Cadmium Exposure in the National Health and Nutrition Examination Survey, 2007–2008: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3569681/
  15. Szczuko et al, Doubtful Justification of the Gluten-Free Diet in the Course of Hashimoto’s Disease: https://www.mdpi.com/2072-6643/14/9/1727
  16. Frank -Raue et al, Thyroid Dysfunction in Peri-and Postmenopausal Women — Cumulative Risks: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10398375/
  17. Tutal et al, Systematic review of COVID-19 and autoimmune thyroiditis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8930178/
  18. Tran et al, The effect of thyroid dysfunction on breast cancer risk: an updated meta-analysis: https://erc.bioscientifica.com/view/journals/erc/30/1/ERC-22-0155.xml
  19. Ibid
  20. Triggiani et al, Role of Iodine, Selenium and Other Micronutrients in Thyroid Function and Disorders: https://www.eurekaselect.com/article/29804
  21. Sathyapalan et al, The Effect of High Dose Isoflavone Supplementation on Serum Reverse T3 in Euthyroid Men with Type 2 Diabetes and Post-menopausal Women: https://www.frontiersin.org/articles/10.3389/fendo.2018.00698/full
  22. Leung et al, History of U.S. Iodine Fortification and Supplementation: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509517/
  23. Arab et al, Pesticides and insulin resistance-related metabolic diseases: Evidences and mechanisms: https://www.sciencedirect.com/science/article/abs/pii/S0048357523001864?via%3Dihub
  24. Wu et al, Metabolic Inflammation and Insulin Resistance in Obesity: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.119.315896
  25. Pappolla et al, Metabolic Inflammation and Insulin Resistance in Obesity: https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.119.315896
  26. Fernandes et al, Insulin resistance in depression: A large meta-analysis of metabolic parameters and variation: https://pubmed.ncbi.nlm.nih.gov/35777578/
  27. Medina et al, Metabolic syndrome, autoimmunity and rheumatic diseases: https://www.sciencedirect.com/science/article/abs/pii/S1043661817313348
  28. Las Heras et al, Relevance of mitochondrial dysfunction in heart disease associated with insulin resistance conditions: https://pubmed.ncbi.nlm.nih.gov/34807312/
  29. Talbot, Brain insulin resistance in Alzheimer's disease and its potential treatment with GLP-1 analogs: https://pubmed.ncbi.nlm.nih.gov/24640977/
  30. Marmol et al, Insulin resistance in patients with cancer: a systematic review and meta-analysis: https://pubmed.ncbi.nlm.nih.gov/37042166/
  31. Proietto, Mechanisms of insulin resistance caused by nutrient toxicity: https://www.sciencedirect.com/science/article/abs/pii/S1386634605002974?via%3Dihub
  32. Yaribeygi et al, Molecular mechanisms linking stress and insulin resistance: https://www.excli.de/index.php/excli/article/view/4382
  33. Masoumi et al, Radiofrequency radiation emitted from Wi-Fi (2.4 GHz) causes impaired insulin secretion and increased oxidative stress in rat pancreatic islets: https://pubmed.ncbi.nlm.nih.gov/29913098/
  34. Graham et al, Maternal Cortisol Concentrations During Pregnancy and Sex Specific Associations with Neonatal Amygdala Connectivity and Emerging Internalizing Behaviors: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632079/
  35. Trump et al, Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation: https://www.nature.com/articles/srep28616
  36. Serpeloni et al, Grandmaternal stress during pregnancy and DNA methylation of the third generation: an epigenome-wide association study: https://www.nature.com/articles/tp2017153
  37. Apprato et al, Natural Epigenetic Modulators of Vitamin D Receptor: https://www.mdpi.com/2076-3417/10/12/4096
  38. Kalilman, Epigenetics and Meditation: https://www.sciencedirect.com/science/article/abs/pii/S2352250X18301817
  39. Zychowska et al, Fasting and Exercise Induce Changes in Serum Vitamin D Metabolites in Healthy Men: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8226906/
  40. Reiter et al, Mitochondria: Central Organelles for Melatonin's Antioxidant and Anti-Aging Actions: https://pubmed.ncbi.nlm.nih.gov/29495303/
  41. Bondy, Melatonin and Aging: https://pubmed.ncbi.nlm.nih.gov/37120473/
  42. Melone et al, Disruption of the circadian rhythm of melatonin: A biomarker of critical illness severity: https://pubmed.ncbi.nlm.nih.gov/37541132/
  43. Beaupre et al, Melatonin’s neuroprotective role in mitochondria and its potential as a biomarker in aging, cognition and psychiatric disorders: https://www.nature.com/articles/s41398-021-01464-x
  44. Reiter et al, Melatonin and its Relation to the Immune System and Inflammation: https://nyaspubs.onlinelibrary.wiley.com/doi/10.1111/j.1749-6632.2000.tb05402.x
  45. Tobeiha et al, Evidence for the Benefits of Melatonin in Cardiovascular Disease: https://www.frontiersin.org/articles/10.3389/fcvm.2022.888319/full
  46. Roa et al, Effects of Melatonin Alone or Associated with Acyclovir on the Suppressive Treatment of Recurrent Genital Herpes: A Prospective, Randomized, and Double-Blind Study: https://www.mdpi.com/2227-9059/11/4/1088
  47. Sharma et al, The role of melatonin in diabetes: therapeutic implications: https://www.scielo.br/j/aem/a/fLyNYxJGWVcgDRm4wbSs3QS/?lang=en
  48. Lingas, A Narrative Review of the Carcinogenic Effect of Night Shift and the Potential Protective Role of Melatonin: https://www.cureus.com/articles/170097-a-narrative-review-of-the-carcinogenic-effect-of-night-shift-and-the-potential-protective-role-of-melatonin#!/
  49. Mankhong et al, Melatonin and Exercise Counteract Sarcopenic Obesity through Preservation of Satellite Cell Function: https://www.mdpi.com/1422-0067/24/7/6097#
  50. Lee et al, The Neuroprotective Effects of Melatonin: Possible Role in the Pathophysiology of Neuropsychiatric Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826722/
  51. Esposito et al, Antiinflammatory Activity of Melatonin in Central Nervous System: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001216/
  52. Alghamdi, The neuroprotective role of melatonin in neurological disorders: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001545/
  53. Esposito et al, Antiinflammatory Activity of Melatonin in Central Nervous System: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001216/
  54. Wang et al, Use of Melatonin in Cancer Treatment: Where Are We?: https://www.mdpi.com/1422-0067/23/7/3779

Chapter 13

  1. Cable et al, Physiology, Progesterone: https://www.ncbi.nlm.nih.gov/books/NBK558960/
  2. Afshari et al, Effect of COVID‐19 infection on sex hormone levels in hospitalized patients: A prospective longitudinal study in Iran: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9789677/
  3. Steward et al, Long COVID risk: a signal to address sex hormones and women's health: https://www.thelancet.com/journals/lanepe/article/PIIS2666-7762(21)00228-3/fulltext
  4. Liu eta l, Breast effects of oral, combined 17β-estradiol, and progesterone capsules in menopausal women: a randomized controlled trial: https://pubmed.ncbi.nlm.nih.gov/32842052/
  5. Barbagallo et al, Vascular Effects of Progesterone: https://www.ahajournals.org/doi/10.1161/01.HYP.37.1.142
  6. Prior, Progesterone as a Bone-Trophic Hormone: https://academic.oup.com/edrv/article-abstract/11/2/386/2548587?redirectedFrom=fulltext&login=false
  7. Ruiz et al, Effectiveness of compounded bioidentical hormone replacement therapy: an observational cohort study: https://pubmed.ncbi.nlm.nih.gov/21651797/
  8. Progesterone selectively increases amygdala reactivity in women: https://www.nature.com/articles/4002030
  9. Manson et al, The New England Journal of Medicine, Estrogen plus Progestin and the Risk of Coronary Heart Disease: https://www.nejm.org/doi/pdf/10.1056/nejmoa030808
  10. Greco et al, Phytoprogestins: Unexplored Food Compounds with Potential Preventive and Therapeutic Effects in Female Disease: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8705436/
  11. Mahboubi, Evening Primrose (Oenothera biennis) Oil in Management of Female Ailments: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6718646/
  12. Li et al, The Role of Plant Progesterone in Regulating Growth, Development and Biotic/Abiotic Stress Responses: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9501841/
  13. Wingen et al, Testosterone Increases Amygdala Reactivity in Middle-Aged Women to a Young Adulthood Level: https://www.nature.com/articles/npp20082#citeas
  14. Donovitz, A Personal Prospective on Testosterone Therapy in Women – What We Know in 2022: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331845/
  15. Donovitz, Low complication rates of testosterone and estradiol implants for androgen and estrogen replacement therapy in over 1 million procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165877/
  16. Scott, Should we be prescribing testosterone to perimenopausal and menopausal women? A guide to prescribing testosterone for women in primary care: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098532/
  17. Sutherland et al, Vitamin D Deficiency Increases Mortality Risk in the UK Biobank: https://www.acpjournals.org/doi/10.7326/M21-3324
  18. Donovitz, A Personal Prospective on Testosterone Therapy in Women —What We Know in 2022: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9331845/
  19. Rochira et al, Role of Estrogens in Male Reproduction: https://www.ncbi.nlm.nih.gov/books/NBK278933/#estrogens-male-repro.ROLE_OF_ESTROGENS_I
  20. Ryczkowska et al, Menopause and women’s cardiovascular health: is it really an obvious relationship?: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10074318/
  21. Borras et al, Direct antioxidant and protective effect of estradiol on isolated mitochondria: https://www.sciencedirect.com/science/article/pii/S092544390900218X
  22. Lejri et al, Mitochondria, Estrogen and Female Brain Aging: https://www.frontiersin.org/articles/10.3389/fnagi.2018.00124/full
  23. Guajardo-Correa et al, Estrogen signaling as a bridge between the nucleus and mitochondria in cardiovascular diseases: https://pubmed.ncbi.nlm.nih.gov/36187489/
  24. Cavalieri et al, Estrogens as endogenous genotoxic agents – DNA adducts and mutations: https://pubmed.ncbi.nlm.nih.gov/10963621/
  25. Vooijs et al, Review of the endometrial safety during intravaginal treatment with estriol: https://www.sciencedirect.com/science/article/abs/pii/030121159502170C
  26. Qureshi et al, The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development: https://www.sciencedirect.com/science/article/pii/S1550413120302473
  27. Miao et al, 4-Hydroxy estrogen metabolite, causing genomic instability by attenuating the function of spindle-assembly checkpoint, can serve as a biomarker for breast cancer: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731443/
  28. Aduse-Poku et al, Associations of Total Body Fat Mass and Skeletal Muscle Index with All-Cause and Cancer-Specific Mortality in Cancer Survivors: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9953880/
  29. Cao et al, Association of Body Fat Distribution and Risk of Breast Cancer in Pre- and Postmenopausal Women: https://karger.com/ofa/article/16/4/356/836871/Association-of-Body-Fat-Distribution-and-Risk-of
  30. Mair et al, Obesity, estrogens and adipose tissue dysfunction – implications for pulmonary arterial hypertension: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7506791/
  31. Kang et al, Regulation of gene expression by 17β-estradiol in the arcuate nucleus of the mouse through ERE-dependent and ERE-independent mechanisms: https://www.sciencedirect.com/science/article/abs/pii/S0039128X16000040?via%3Dihub
  32. Hayashi et al, Physiological Concentration of 17β-Estradiol Retards the Progression of Severe Atherosclerosis Induced by a High-Cholesterol Diet Plus Balloon Catheter Injury: https://www.ahajournals.org/doi/10.1161/01.ATV.20.6.1613
  33. Chidi-Ogbolu et al, Effect of Estrogen on Musculoskeletal Performance and Injury Risk: https://www.frontiersin.org/articles/10.3389/fphys.2018.01834/full
  34. Nishibe et al, Effect of estriol and bone mineral density of lumbar vertebrae in elderly and postmenopausal women: https://pubmed.ncbi.nlm.nih.gov/8741364/#:~:text=Although%20a%20lower%20dosage%20of,are%20also%20responsive%20to%20estriol
  35. Voskuhl et al, Estriol combined with glatiramer acetate for women with relapsing-remitting multiple sclerosis: a randomised, placebo-controlled, phase 2 trial: https://www.thelancet.com/journals/laneur/article/PIIS1474-4422(15)00322-1/fulltext
  36. Vooijs, Review of the endometrial safety during intravaginal treatment with estriol: https://www.sciencedirect.com/science/article/abs/pii/030121159502170C
  37. Mattsson, Safety and tolerability of pulsed estrogen therapy: key factors for an improved compliance: https://pubmed.ncbi.nlm.nih.gov/12482110/
  38. Lejri et al, Mitochondria, Estrogen and Female Brain Aging: https://www.frontiersin.org/articles/10.3389/fnagi.2018.00124/full
  39. Hao et al, Age at Menopause and All-Cause or Cause-Specific Dementia: https://pubmed.ncbi.nlm.nih.gov/37344154/
  40. Farruggio et al, Genistein improves viability, proliferation and mitochondrial function of cariomyoblasts cultured in physiologic and peroxidative conditions: https://www.spandidos-publications.com/10.3892/ijmm.2019.4365
  41. Wu et al, Genistein Improves Bone-Healing: https://pubmed.ncbi.nlm.nih.gov/32897066/
  42. Sharifi-Rad et al, Genistein: An Integrative Overview of its Mode of Action, Pharmacological Properties, and Health Benefits: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8315847/
  43. Li et al, Dietary Mushroom Intake May Reduce the Risk of Breast Cancer: https://pubmed.ncbi.nlm.nih.gov/24691133/
  44. Patel et al, Estrogen: The necessary evil for human health, and ways to tame it: https://pubmed.ncbi.nlm.nih.gov/29573619/
  45. Xu et al, Estrogen Receptors in Polycystic Ovary Syndrome: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7924872/
  46. Guinter et al, A dietary pattern based on estrogen metabolism is associated with breast cancer risk in a prospective cohort of postmenopausal women: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6019153/
  47. Arslan et al, Circulating Estrogen Metabolites and Risk of Breast Cancer in Postmenopausal Women: https://aacrjournals.org/cebp/article/23/7/1290/70642/Circulating-Estrogen-Metabolites-and-Risk-of
  48. Ibid.
  49. Lejri et al, Mitochondria, Estrogen and Female Brain Aging: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5934418/
  50. Suojanen et al, Influence of estrogen on glutathione levels and glutathione-metabolizing enzymes in uteri and R3230AC mammary tumors of rats: https://www.sciencedirect.com/science/article/abs/pii/0304416580900033
  51. Sheng-Huang et al, Effects of estrogen on glutathione and catalase levels in human erythrocyte during menstrual cycle: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360843/
  52. Semenova et al, Glutathione Component of Antioxidant Status in Menopausal Women with Insomnia: https://pubmed.ncbi.nlm.nih.gov/36322310/
  53. Ibid
  54. Ali et al, The Role of Estrogen Therapy as a Protective Factor for Alzheimer’s Disease and Dementia in Postmenopausal Women: A Comprehensive Review of the Literature: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10480684/
  55. Pizzorno, Glutathione! https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4684116/
  56. Minich et al, A Review of Dietary (Phyto)Nutrients for Glutathione Support: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770193/
  57. Musazadeh et al, Flaxseed Oil Supplementation Augments Antioxidant Capacity and Alleviates Oxidative Stress: A Systematic Review and Meta-Analysis of Randomized Controlled Trials: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8437595/
  58. Lana et al, Nebulization of glutathione and N-acetylcysteine as an adjuvant therapy for COVID-19 onset: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8349474/

Chapter 14

  1. Compilations, The Compilations of Compilations, Volume 1, p. 85: https://bahai-library.com/pdf/compilations/conservation.pdf
  2. Nerattini et al, Systematic review and meta-analysis of the effects of menopause hormone therapy on risk of Alzheimer’s disease and dementia: https://www.frontiersin.org/articles/10.3389/fnagi.2023.1260427/full
  3. Daniel et al, Cardiometabolic health, menopausal estrogen therapy and the brain: How effects of estrogens diverge in healthy and unhealthy preclinical models of aging: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10725785/
  4. Abdi et al, The Effects of Transdermal Estrogen Delivery on Bone Mineral Density in Postmenopausal Women: A Meta-analysis: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5423263/
  5. Donovitz, Low complication rates of testosterone and estradiol implants for androgen and estrogen replacement therapy in over 1 million procedures: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8165877/
  6. Writing Group for the Women’s Health Initiative Investigators: Risks and Benefits of Estrogen Plus Progestin in Healthy Postmenopausal Women: https://jamanetwork.com/journals/jama/fullarticle/195120
  7. Holtorf, The bioidentical hormone debate: are bioidentical hormones (estradiol, estriol, and progesterone) safer or more efficacious than commonly used synthetic versions in hormone replacement therapy?: https://pubmed.ncbi.nlm.nih.gov/19179815/

Chapter 15

  1. Heimrich et al, What Determines That Older Adults Feel Younger Than They Are? Results From a Nationally Representative Study in Germany: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9274253/
  2. Langer, Counterclockwise: Mindful Health and the Power of Possibility: https://experiencelife.lifetime.life/wp-content/uploads/2021/06/Nov15_OL_Counterclockwise.pdf
  3. Otin et al, Hallmarks of Aging: An expanding universe: https://www.sciencedirect.com/science/article/pii/S0092867422013770#fig1
  4. Schumacher et al, The central role of DNA damage in the ageing process: https://www.nature.com/articles/s41586-021-03307-7
  5. Lopez-Otin et al, Hallmarks of aging: An expanding universe: https://www.sciencedirect.com/science/article/abs/pii/S0092867422013770#preview-section-snippets
  6. Sellami et al, Regular, Intense Exercise Training as a Healthy Aging Lifestyle Strategy: Preventing DNA Damage, Telomere Shortening and Adverse DNA Methylation Changes Over a Lifetime: https://www.frontiersin.org/articles/10.3389/fgene.2021.652497/full
  7. Karsono et al, Potential Antiaging Effects of DLBS1649, a Centella asiatica Bioactive Extract: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8369046/
  8. Rio et al, Olive oil and the Hallmarks of Aging: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6273542/
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https://www.frontiersin.org/articles/10.3389/fnut.2021.655038/full

Chapter 16

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